In this randomized controlled trial of IV alteplase for ischemic stroke, researchers evaluated CT or brain MRI scans before treatment and 24 to 48 hours after treatment for acute lesion visibility, extent, and swelling.
Article Correctness Is Author's Responsibility: Vagus Nerve Stimulation Superior to Sham Device for Acute Migraine Treatment
Researchers sought to determine whether noninvasive vagus nerve stimulation significantly reduces the amount of pain or even takes pain away entirely in patients with episodic migraine.
Article Correctness Is Author's Responsibility: Cognitive Decline Worsens With Memantine, ChEIs in Patients With Alzheimer’s
The concomitant use of cholinesterase inhibitors or memantine was associated with an increased rate of cognitive decline in clinical trials of patients with Alzheimer disease.
Article Correctness Is Author's Responsibility: Bafiertam Gets Tentative Approval for Relapsing Multiple Sclerosis
Bafiertam is a new fumarate bioequialent alternative to its prodrug, Tecfidera (dimethyl fumarate; Biogen).
Article Correctness Is Author's Responsibility: Relapsing MS: Greater Treatment Satisfaction Following Switch to Teriflunomide
Investigators reviewed patient-reported outcomes to assess treatment satisfaction with teriflunomide and also looked at feedback from physicians regarding the effectiveness of teriflunomide when used in routine clinical practice.
Article Correctness Is Author's Responsibility: Race May Affect Phenotype, Age of Onset, and Severity of Neuromyelitis Optica Spectrum Disorder
Investigators analyzed racial differences in the clinical features of neuromyelitis optica spectrum disorder.
Article Correctness Is Author's Responsibility: Hospital Infections Increase 30-Day Readmission Rates in Patients With Stroke
Investigators examined the effect of common infections such as urinary tract infections, sepsis, and pneumonia on >300,000 patients with ischemic stroke.
Article Correctness Is Author's Responsibility: Infratentorial Lesions Beneficial for Differentiating Fabry Disease vs MS
Investigators sought to determine whether absence of lesions in 2 specific brain regions can distinguish Fabry disease from multiple sclerosis.
Article Correctness Is Author's Responsibility: Very Early Mobilization After Stroke Does Not Improve Survival Over Usual Care
Investigators examined whether very early mobilization, started ?48 hours after onset of stroke symptoms, improves recovery and survival after stroke compared with more delayed mobilization.
Article Correctness Is Author's Responsibility: Migraine With Aura Increases Risk for Carotid Thickening in Middle-Aged Women
Migraine with aura increased the risk for diffuse carotid thickening and migraine without aura was associated with a low risk for carotid plaques and arterial stiffening in middle-aged women.
Article Correctness Is Author's Responsibility: Alemtuzumab Linked to Clinical and MRI Disease Remission in Multiple Sclerosis
Researchers evaluated clinical and magnetic resonance imaging data from patients with relapsing-remitting multiple sclerosis treated with alemtuzumab.
Article Correctness Is Author's Responsibility: Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy
Investigators examined whether a bracelet capable of measuring heart rate and movement would be beneficial for detecting nocturnal seizures in patients with epilepsy.
Article Correctness Is Author's Responsibility: Nocturnal Seizures With Convulsions Linked to SUDEP
Investigators sought to predict the incidence of SUDEP in people with intellectual disabilities in residential care settings and to determine its relationship with nocturnal seizures and nocturnal supervision.
Article Correctness Is Author's Responsibility: Movement Execution Induces STDT Changes With Focal Dystonias
The use of somatosensory temporal discrimination testing did not incite any changes in the mean velocity of index finger movements in either patients with dystonia or healthy controls.
Article Correctness Is Author's Responsibility: Pregnancy Rates Among Patients With MS Rise Despite More Peripartum Issues
Investigators retrospectively reviewed data to compare pregnancy prevalence and complications in women with and without multiple sclerosis.
Article Correctness Is Author's Responsibility: Premenopausal Bilateral Salpingo-Oophorectomy and Medial Temporal Lobe Issues
Investigators analyzed medial temporal lobe structure, white matter lesion load, and ?-amyloid deposition in women who underwent bilateral salpingo-oophorectomy prior to reaching natural menopause.
Article Correctness Is Author's Responsibility: Cervical Dysfunction Needs Clarification to Identify Link With Headache
Future research is needed to determine whether cervical musculoskeletal dysfunction causes migraine or tension-type headache-related neck pain.
Article Correctness Is Author's Responsibility: MRI Markers Associated With Increased Risk for Stroke, Dementia, Death in Older Adults
Systematic review and meta-analysis provides evidence that white matter hyperintensities, brain infarcts, and cerebral microbleeds indicate a significant increased risk for stroke, dementia, and death in community-dwelling older adults.
Article Correctness Is Author's Responsibility: Clinicians Must Do Their Part to Address Inaccurate Online Health Information
Clinicians have a responsibility to engage in initiatives that improve the quality of health information available online.
Article Correctness Is Author's Responsibility: FDG-PET Imaging Reliable in Identifying Abnormalities in Parkinson Disease
Researchers performed contrast analysis on different imaging modalities and cross-validated results using a “unique approach integrating two meta-analytical algorithms.”