Researchers retrospectively reviewed data regarding children and youths who were beginning treatment with antipsychotic vs control medications to assess their risks for unexpected death.
The co-occurrence of obesity and mood disorders increases the risk for physical comorbidities, poor mental health and psychological well-being, and less healthy behaviors.
Although treatment as usual for psychosis is guideline-congruent and well implemented, there appears to be no added value for adjunct cognitive behavioral therapy for social activation, according to the results of a study from the Netherlands.
Symptoms of depression and PTSD may be increased in veterans with insomnia, which may be associated with an increased risk for suicidal behavior.
In the Phase 3 JET8 study (N=318), patients underwent a circadian challenge of 8 hours in advance to their usual bedtime.
Investigators determined that although psychotropic medication review may reduce the number of prescriptions dispensed, clinical and economic benefits have yet to be identified; therefore, they do not recommend medication review as part of routine care.
In this study of older patients with schizophrenia, investigators examined the temporal fluctuations that occur with awareness of mental illness, and related factors that influence illness awareness.
Alprazolam was found to be the most commonly misused benzodiazepine.
An NDA has been submitted to the FDA for a transdermal patch formulation of asenapine for the treatment of schizophrenia.
Investigators sought to determine clinical characteristics associated with an increased risk for mild cognitive impairment in older adults with depression.
An authorized generic version of Evzio is expected to be available next year at a price of $178 per carton.
Sandoz and Pear Therapeutics announced that the FDA has granted clearance for reSET-O, the first prescription digital therapeutic for patients with opioid use disorder.
Genetic risk from rare copy number variants and common single-nucleotide polymorphisms may contribute to liability to schizophrenia.
RCADS is often used to measure anxiety and depression and researchers assessed its structural validity for adults, given the life span nature of anxiety.
Investigators examined the efficacy of sertraline and interpersonal psychotherapy vs pill placebo over 12 weeks in woman with postpartum depression.
Lumateperone and follow-on compounds are also being evaluated for bipolar depression, behavioral disturbance associated with dementia, sleep disturbances associated with neuropsychiatric disorders, and other neuropsychiatric conditions including major …
The use of a polygenic risk score for schizophrenia can effectively predict an antipsychotic treatment response after a first episode of psychosis.
The use of ezogabine, a KCNQ channel opener, may improve depression and anhedonic symptoms in patients with major depressive disorder.
Psychotic experiences may be a clinical marker of risk for future suicidal behaviors.
Mindfulness meditation training may reduce negative affect variability in middle-age and older adults.